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Bruins Vs Sabres Prediction, Picks & Odds For Tonight’s Nhl Game

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Tage Thompson is one of the best volume shooters in the sport, ranking seventh in shot attempts and eighth in shots on target.

My Bruins vs. Sabres predictions expect his shooting opportunities to be plentiful against a fatigued side that bleeds shots at the best of times.

Let’s dive into my NHL picks for Wednesday, March 25.

Bruins vs Sabres prediction

Bruins vs Sabres best bet: Tage Thompson Over 3.5 shots on goal (-105)

Tage Thompson is a Boston Bruins killer. He has recorded 4+ shots on goal in six consecutive games while averaging 6.16 per contest.

That includes two head-to-head meetings this season, which should come as no surprise given the Bruins rank 31st in shots allowed.

Thompson has also cleared 3.5 shots in eight of 11 home games against Bottom-10 shot suppression teams. The three Unders came in multi-goal victories vs. teams 27th or lower in the standings, leaving no reason for Thompson to push.

With first place in the Eastern Conference within reach, the Buffalo Sabres will lean heavily on Thompson in this matchup.

Bruins vs Sabres same-game parlay

Josh Doan has produced an average of 2.5 shots and cleared his line in 10 of 11 home games against Bottom-10 shot suppression teams. He has fared particularly well against the Bruins this season, generating 6+ shot attempts in both meetings.

Josh Norris is riding shotgun with Doan on a strong third line and also skates on the top power play, making him a prime candidate to hit the scoresheet. He has done so in four of five games this season following two days of rest.

Bruins vs Sabres SGP

  • Tage Thompson Over 3.5 shots on goal
  • Josh Doan Over 1.5 shots on goal
  • Josh Norris Over 0.5 points

Bruins vs Sabres odds

  • Moneyline: Bruins +160 | Sabres -190
  • Puck Line: Bruins +1.5 (-145) | Sabres -1.5 (+125)
  • Over/Under: Over 6.5 (-110) | Under 6.5 (-110)

Bruins vs Sabres trend

Josh Doan has registered multiple shots on goal in 10 consecutive games. Find more NHL betting trends for Bruins vs. Sabres.

How to watch Bruins vs Sabres

LocationKeyBank Center, Buffalo, NY
DateWednesday, March 25, 2026
Puck drop7:30 p.m. ET
TVNESN, MSG-B

Bruins vs Sabres latest injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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